Protein Name | cytochrome P450 family 7 subfamily A member 1 |
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Organism | Rattus norvegicus |
Gene ID | 25428 |
Gene Symbol | Cyp7a1 |
UniProt | P18125 (CP7A1_RAT) |
Relationships |
Total Number of functionally related compound(s) :
217
Total Number of Articles : 395 |
Description |
cytochrome P450 family 7 subfamily A member 1 |
Gene Summary |
Enables cholesterol 7-alpha-monooxygenase activity. Involved in several processes, including cellular response to cholesterol; regulation of lipid biosynthetic process; and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Biomarker of alcoholic hepatitis; cholestasis; extrahepatic cholestasis; and metabolic dysfunction-associated steatohepatitis. Orthologous to human CYP7A1 (cytochrome P450 family 7 subfamily A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |