Protein Name cytochrome P450 family 7 subfamily A member 1
Organism Rattus norvegicus
Gene ID 25428
Gene Symbol

Cyp7a1

UniProt P18125 (CP7A1_RAT)
Relationships Total Number of functionally related compound(s) : 217
Total Number of Articles : 395
Description

cytochrome P450 family 7 subfamily A member 1

Gene Summary

Enables cholesterol 7-alpha-monooxygenase activity. Involved in several processes, including bile acid biosynthetic process; cellular response to cholesterol; and regulation of lipid biosynthetic process. Located in intracellular membrane-bounded organelle. Biomarker of alcoholic hepatitis; cholestasis; extrahepatic cholestasis; and non-alcoholic steatohepatitis. Orthologous to human CYP7A1 (cytochrome P450 family 7 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 7A1
  • 24-hydroxycholesterol 7-alpha-hydroxylase
  • CYPVII
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Properties