Pub. Date : 1995 Feb 1
PMID : 7833476
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fibrinogen inhibits the heparin cofactor II-mediated antithrombin activity of dermatan sulfate. | Dermatan Sulfate | serpin family C member 1 | Homo sapiens |
| 2 | The antithrombin activity of several dermatan sulfate preparations has been measured in whole human plasma and found to be -55% of that in purified systems. | Dermatan Sulfate | serpin family C member 1 | Homo sapiens |
| 3 | Kinetic studies under pseudo-first-order conditions indicated that the reduction in antithrombin activity of dermatan sulfate in plasma compared with that in buffer was due to noncompetitive inhibition with respect to dermatan sulfate. | Dermatan Sulfate | serpin family C member 1 | Homo sapiens |
| 4 | Kinetic studies under pseudo-first-order conditions indicated that the reduction in antithrombin activity of dermatan sulfate in plasma compared with that in buffer was due to noncompetitive inhibition with respect to dermatan sulfate. | Dermatan Sulfate | serpin family C member 1 | Homo sapiens |
| 5 | Addition of these proteins to the purified system showed that only fibrinogen inhibited the antithrombin activity of dermatan sulfate and that it did so in a concentration-dependent manner over the physiologic range of plasma fibrinogen levels. | Dermatan Sulfate | serpin family C member 1 | Homo sapiens |