Title : Cyclooxygenase inhibitors enhance tumour necrosis factor production and mortality in murine endotoxic shock.

Pub. Date : 1994 Sep

PMID : 7827287






1 Functional Relationships(s)
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1 These results indicate that TNF-alpha production is modulated by endogenous prostaglandins in vivo and that enhanced production of TNF-alpha by cyclooxygenase inhibitors may lead to exacerbation of some inflammatory processes. Prostaglandins tumor necrosis factor Mus musculus