Title : Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos: with and without diazepam pretreatment.

Pub. Date : 1995 Jan

PMID : 7823174






3 Functional Relationships(s)
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1 Diazepam also produced dose-related decreases in conditioned stress-induced c-fos expression in all but one structure, the effects being statistically significant in 38 of 60 sampled structures. Diazepam Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Diazepam dose dependently increased fear-induced c-fos expression in the central nucleus of the amygdala. Diazepam Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 The extent to which diazepam decreased conditioned stress-induced c-fos expression was unrelated to previous estimates of benzodiazepine receptor density in the sampled structures. Diazepam Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus