Title : The activation of phosphatidylinositol 3-kinase by Ras.

Pub. Date : 1994 Sep 1

PMID : 7820549






1 Functional Relationships(s)
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1 The phenotype induced by v-Ras was consistent with activation of the p85 alpha/p110 alpha complex: it was sensitive to the phosphatidylinositol 3-kinase inhibitor, wortmannin, and the cells accumulated 3-phosphorylated polyphosphoinositides. Wortmannin phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens