Title : Prion protein and the scrapie agent: in vitro studies in infected neuroblastoma cells.

Pub. Date : 1994 Apr-Jun

PMID : 7812655






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 With this in vitro system, Congo red and several sulfated polysaccharides, including heparin and pentosan polysulfate, were found to inhibit accumulation of protease-resistant PrP. Heparin prion protein Homo sapiens
2 These results and additional data confirming PrP binding to heparin suggested a possible role for sulfated glycosaminoglycans in the generation of protease-resistant PrP during scrapie infection. Heparin prion protein Homo sapiens
3 These results and additional data confirming PrP binding to heparin suggested a possible role for sulfated glycosaminoglycans in the generation of protease-resistant PrP during scrapie infection. Heparin prion protein Homo sapiens