Title : Endothelin-1 modulates renin and prolactin release from human decidua by different mechanisms.

Pub. Date : 1994 Dec

PMID : 7810625






2 Functional Relationships(s)
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1 Calcium ionophore A-23187 stimulated basal renin release and potentiated ET-1-stimulated renin release but had no effect on basal or ET-inhibited PRL release. Calcium endothelin 1 Homo sapiens
2 These results indicate that the effects of ET-1 on both decidual renin and PRL release are dependent on the activation of protein kinase C. However, the effect of ET-1 on renin release appears to be dependent on extracellular calcium, whereas the effect on PRL is not influenced by extracellular calcium. Calcium endothelin 1 Homo sapiens