Title : [Transferrin receptor and iron deposition pattern in the hepatic lobules of the iron-deficient and iron-overloaded rats].

Pub. Date : 1995 Apr

PMID : 7788730






10 Functional Relationships(s)
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1 [Transferrin receptor and iron deposition pattern in the hepatic lobules of the iron-deficient and iron-overloaded rats]. Iron transferrin receptor Rattus norvegicus
2 [Transferrin receptor and iron deposition pattern in the hepatic lobules of the iron-deficient and iron-overloaded rats]. Iron transferrin receptor Rattus norvegicus
3 TfR and Tf were mainly distributed in the peripheral part of the lobule (zone 1) in the normal, iron deficient and iron-overloaded rats. Iron transferrin receptor Rattus norvegicus
4 TfR and Tf were mainly distributed in the peripheral part of the lobule (zone 1) in the normal, iron deficient and iron-overloaded rats. Iron transferrin receptor Rattus norvegicus
5 The staining intensity of TfR was strongest in iron-deficiency rat hepatic cells, weakest in iron-overloaded rat hepatic cells when compared with controls. Iron transferrin receptor Rattus norvegicus
6 In the iron-overloaded rats, the staining intensity of iron was stronger in zone 1 than in zone 2 and 3, similar to the distribution pattern of TfR and Tf. Iron transferrin receptor Rattus norvegicus
7 These findings suggest that (1) iron uptake in hepatic cells in vivo is regulated and mediated by TfR and Tf, (2) the expression pattern of TfR and Tf in zone 1 to zone 3 liver cells may result in the progressive decrease of iron deposition in the hepatic lobules of the iron overloaded rats. Iron transferrin receptor Rattus norvegicus
8 These findings suggest that (1) iron uptake in hepatic cells in vivo is regulated and mediated by TfR and Tf, (2) the expression pattern of TfR and Tf in zone 1 to zone 3 liver cells may result in the progressive decrease of iron deposition in the hepatic lobules of the iron overloaded rats. Iron transferrin receptor Rattus norvegicus
9 These findings suggest that (1) iron uptake in hepatic cells in vivo is regulated and mediated by TfR and Tf, (2) the expression pattern of TfR and Tf in zone 1 to zone 3 liver cells may result in the progressive decrease of iron deposition in the hepatic lobules of the iron overloaded rats. Iron transferrin receptor Rattus norvegicus
10 These findings suggest that (1) iron uptake in hepatic cells in vivo is regulated and mediated by TfR and Tf, (2) the expression pattern of TfR and Tf in zone 1 to zone 3 liver cells may result in the progressive decrease of iron deposition in the hepatic lobules of the iron overloaded rats. Iron transferrin receptor Rattus norvegicus