Protein Name transferrin receptor
Organism Rattus norvegicus
Gene ID 64678
Gene Symbol

Tfrc

UniProt Q99376 (TFR1_RAT)
Relationships Total Number of functionally related compound(s) : 84
Total Number of Articles : 142
Description

transferrin receptor

Gene Summary

Enables Hsp70 protein binding activity; chaperone binding activity; and transferrin receptor activity. Involved in several processes, including response to copper ion; response to manganese ion; and response to retinoic acid. Located in several cellular components, including cell surface; extracellular exosome; and recycling endosome membrane. Biomarker of duodenal ulcer; hepatocellular carcinoma; muscular atrophy; non-alcoholic fatty liver disease; and nutrition disease. Human ortholog(s) of this gene implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian cancer. Orthologous to human TFRC (transferrin receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • transferrin receptor protein 1
  • TR
  • tfR
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Properties