Protein Name | transferrin receptor |
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Organism | Rattus norvegicus |
Gene ID | 64678 |
Gene Symbol | Tfrc |
UniProt | Q99376 (TFR1_RAT) |
Relationships |
Total Number of functionally related compound(s) :
84
Total Number of Articles : 142 |
Description |
transferrin receptor |
Gene Summary |
Enables Hsp70 protein binding activity; chaperone binding activity; and transferrin receptor activity. Involved in several processes, including response to copper ion; response to manganese ion; and response to retinoic acid. Located in several cellular components, including cell surface; extracellular exosome; and recycling endosome membrane. Biomarker of duodenal ulcer; hepatocellular carcinoma; muscular atrophy; non-alcoholic fatty liver disease; and nutrition disease. Human ortholog(s) of this gene implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian cancer. Orthologous to human TFRC (transferrin receptor). [provided by Alliance of Genome Resources, Apr 2022] |
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