Pub. Date : 1995 May 19
PMID : 7744876
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Isolation of a high affinity inhibitor of urokinase-type plasminogen activator by phage display of ecotin. | ecotin | plasminogen activator, urokinase | Homo sapiens |
2 | However, although the catalytic domain of human urokinase-type plasminogen activator (uPA) has 40% identity to bovine trypsin and the substrate specificities of these two proteases are virtually identical, ecotin inhibits uPA almost 10,000-fold less efficiently than trypsin. | ecotin | plasminogen activator, urokinase | Homo sapiens |
3 | However, although the catalytic domain of human urokinase-type plasminogen activator (uPA) has 40% identity to bovine trypsin and the substrate specificities of these two proteases are virtually identical, ecotin inhibits uPA almost 10,000-fold less efficiently than trypsin. | ecotin | plasminogen activator, urokinase | Homo sapiens |