Title : Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide.

Pub. Date : 1995 May 1

PMID : 7729015






1 Functional Relationships(s)
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1 Treatment of RASMCs with hemin and sodium arsenite, which are inducers of HO-1, stimulated RASMC cGMP without stimulating nitrite release or inducible NO synthase expression, and the induced elevations of cGMP were not inhibited by the NO synthase inhibitor NG-methyl-L-arginine. sodium arsenite nitric oxide synthase 2 Rattus norvegicus