Title : Ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) and the tyrphostin ST271 inhibit phospholipase C in human platelets by preventing Ca2+ entry.

Pub. Date : 1995 Apr

PMID : 7723744






1 Functional Relationships(s)
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1 It is concluded that elevation of intracellular Ca2+ regulates agonist-induced activation of phospholipase C and that this contributes to the inhibition of thrombin-induced formation of inositol phosphates by the tyrphostin ST271. Tyrphostins coagulation factor II, thrombin Homo sapiens