Title : Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Pub. Date : 1995 Jan

PMID : 7720520






1 Functional Relationships(s)
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1 The probes sulfaphenazole (CYP2C9) and quinidine (CYP2D6) selectively inhibited tolbutamide methylhydroxylation and bufuralol 1"-hydroxylation, respectively. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens