Title : Structure-function analysis of human alpha 1-->3fucosyltransferases. A GDP-fucose-protected, N-ethylmaleimide-sensitive site in FucT-III and FucT-V corresponds to Ser178 in FucT-IV.

Pub. Date : 1995 Apr 7

PMID : 7713918






2 Functional Relationships(s)
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1 A GDP-fucose-protected, N-ethylmaleimide-sensitive site in FucT-III and FucT-V corresponds to Ser178 in FucT-IV. Guanosine Diphosphate fucosyltransferase 3 (Lewis blood group) Homo sapiens
2 Recombinant forms of both FucT-III and FucT-V were irreversibly inactivated by N-ethylmaleimide and could be effectively protected from inactivation by GDP-fucose and GDP but not by UDP-galactose, fucose, or N-acetyllactosamine. Guanosine Diphosphate fucosyltransferase 3 (Lewis blood group) Homo sapiens