Title : Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR.

Pub. Date : 1993 Dec

PMID : 7693978






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phosphorylation of both wild-type PKR and PKR(K296R) was inhibited in the presence of 2-aminopurine. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
2 Phosphorylation of both wild-type PKR and PKR(K296R) was inhibited in the presence of 2-aminopurine. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
3 This intermolecular phosphorylation of mutant PKR(K296R) by wild-type PKR was dependent on double-stranded RNA and was inhibited by 2-aminopurine. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
4 This intermolecular phosphorylation of mutant PKR(K296R) by wild-type PKR was dependent on double-stranded RNA and was inhibited by 2-aminopurine. 2-Aminopurine eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens