Pub. Date : 1993 Jul
PMID : 7686498
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eumelanin biosynthesis is regulated by coordinate expression of tyrosinase and tyrosinase-related protein-1 genes. | eumelanin | tyrosinase-related protein 1 | Mus musculus |
| 2 | In all cases, the mRNA levels of tyrosinase and TRP-1 changed in parallel with tyrosinase activity and eumelanin content. | eumelanin | tyrosinase-related protein 1 | Mus musculus |
| 3 | These results suggest that the expressions of tyrosinase and TRP-1 genes are coordinately regulated by melanotropic reagents through cAMP-dependent protein kinase and protein kinase C in mouse B16-F1 cells, and that their coordinate expression causes eumelanin biosynthesis. | eumelanin | tyrosinase-related protein 1 | Mus musculus |