| Protein Name | tyrosinase-related protein 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22178 |
| Gene Symbol | Tyrp1 |
| UniProt | P07147 (TYRP1_MOUSE), Q3UFS3 (Q3UFS3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
131
Total Number of Articles : 148 |
Description |
tyrosinase-related protein 1 |
| Gene Summary |
Enables protein homodimerization activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within several processes, including acetoacetic acid metabolic process; melanocyte differentiation; and melanosome organization. Located in melanosome membrane. Is expressed in several structures, including hip; nervous system; sensory organ; skeleton; and skin. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |