Title : The Na+ binding site of thrombin.

Pub. Date : 1995 Sep 22

PMID : 7673182






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutation of two Asp residues flanking Arg221a (D221A/D222K) almost abolishes the allosteric properties of thrombin and shows that the Na+ binding loop is also involved in direct recognition of protein C and antithrombin. Aspartic Acid coagulation factor II, thrombin Homo sapiens