Pub. Date : 1995 Sep
PMID : 7665919
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 2 | Recent studies have shown that topical application of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) to murine skin results in increased expression of the highly inflammatory cytokine interleukin (IL)-1 alpha in the epidermis. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 3 | Recent studies have shown that topical application of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) to murine skin results in increased expression of the highly inflammatory cytokine interleukin (IL)-1 alpha in the epidermis. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 4 | This has led to the suggestion that IL-1 alpha directly or indirectly mediates the inflammatory and hyperplastic responses elicited by TPA and possibly by other skin tumor promoters. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 5 | Northern blot analysis indicated that topical application of TPA, anthralin, mezerein, or benzoyl peroxide to SENCAR mice resulted in an increased expression of epidermal IL-1 alpha mRNA. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 6 | Pretreatment of the skin with GTP or individual epicatechin derivatives (ECDs) present therein, 30 min before that of TPA, resulted in a significant inhibition of enhanced expression of epidermal IL-1 alpha mRNA caused by skin application of TPA. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |
| 7 | Pretreatment of the skin with GTP or individual epicatechin derivatives (ECDs) present therein, 30 min before that of TPA, resulted in a significant inhibition of enhanced expression of epidermal IL-1 alpha mRNA caused by skin application of TPA. | Tetradecanoylphorbol Acetate | interleukin 1 alpha | Mus musculus |