Title : Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil.

Pub. Date : 1995 Aug 11

PMID : 7642571






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil. Fluorouracil thymidine phosphorylase Homo sapiens
2 A likely mechanism for this action is the induction by IFN alpha of thymidine phosphorylase (TP), the first enzyme in one pathway for the metabolic activation of FUra to fluorodeoxyribonucleotides. Fluorouracil thymidine phosphorylase Homo sapiens