Title : Developmental changes predispose the fetal thymus to positive selection of CD4+CD8- T cells.

Pub. Date : 1995 Jun

PMID : 7642219






1 Functional Relationships(s)
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1 Importantly, day 16 thymocytes transferred to day 14 deoxyguanosine-treated rudiments are likewise arrested at the CD4+CD8+ stage, suggesting that the thymic microenvironment of day 14 rudiments, rather than the state of differentiation of the thymocytes they contain, is responsible for the block in positive selection. Deoxyguanosine CD4 molecule Homo sapiens