Title : N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.

Pub. Date : 1995 Mar

PMID : 7628308






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Recombinant CYP2C9 catalyzed the N-hydroxylation of SMX. Sulfamethoxazole cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 SMX-HA formation in human hepatic microsomes was therefore mediated predominantly by CYP2C9. Sulfamethoxazole cytochrome P450 family 2 subfamily C member 9 Homo sapiens