Title : Acute increase of GABAergic neurotransmission exerts a stimulatory effect on GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized, estrogen- and progesterone-treated adult female rats.

Pub. Date : 1995 May

PMID : 7617125






1 Functional Relationships(s)
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1 Activation of GABA-A receptor with muscimol at a low dose (5 nmol) but not at high doses (10 and 30 nmol) elevated GnRH mRNA levels by 60% over the control value. Muscimol gonadotropin releasing hormone 1 Rattus norvegicus