Pub. Date : 1995 Feb
PMID : 7608126
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genes involved in the phospholipid synthesis of Saccharomyces cerevisiae, such as PEM1, PEM2, PSS, and INO1, are coordinately repressed by myo-inositol and choline. | Inositol | inositol-3-phosphate synthase INO1 | Saccharomyces cerevisiae S288C |
| 2 | Analysis using various lacZ fusion constructs containing promoters for genes in phospholipid synthesis revealed that the expression of myo-inositol-choline-regulated genes, PEM1, PEM2, PSS, CKI, and INO1, was markedly decreased in the snf2/swi2/gam1/tye3/ric1 background, but the expression of a constitutive gene, PIS, was not. | Inositol | inositol-3-phosphate synthase INO1 | Saccharomyces cerevisiae S288C |
| 3 | We conclude that SNF2/SWI2/GAM1/TYE3/RIC1 is a positive regulatory gene required for the expression of not only INO1 gene, but also of myo-inositol-choline-regulated genes in general. | Inositol | inositol-3-phosphate synthase INO1 | Saccharomyces cerevisiae S288C |