Title : p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors.

Pub. Date : 1995 Nov

PMID : 7589239






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Downregulation of p125FAK tyrosine phosphorylation is observed by treating cells with cytochalasin D (CD), a drug known to rapidly disrupt the actin cytoskeleton. Cytochalasin D protein tyrosine kinase 2 Homo sapiens
2 Downregulation of p125FAK tyrosine phosphorylation is observed by treating cells with cytochalasin D (CD), a drug known to rapidly disrupt the actin cytoskeleton. Cytochalasin D protein tyrosine kinase 2 Homo sapiens
3 When PTPase inhibitors are added in combination to CD, the level of tyrosine phosphorylation of p125FAK remains high and focal adhesions and actin stress fibers are preserved from the CD-mediated disruption. Cytochalasin D protein tyrosine kinase 2 Homo sapiens