Pub. Date : 1995 Jan-Mar
PMID : 7588997
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [125I]-Labeled thrombin was incubated with human plasma and its interactions with the two plasma protease inhibitors antithrombin III (AT-III) or heparin cofactor II (HC-II) were investigated in the presence of oat spelts xylan sulfate (OSXS), sodium pentosan polysulfate (SP-54), and the results were compared with heparin and dermatan sulfate. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 2 | [125I]-Labeled thrombin was incubated with human plasma and its interactions with the two plasma protease inhibitors antithrombin III (AT-III) or heparin cofactor II (HC-II) were investigated in the presence of oat spelts xylan sulfate (OSXS), sodium pentosan polysulfate (SP-54), and the results were compared with heparin and dermatan sulfate. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 3 | [125I]-Labeled thrombin was incubated with human plasma and its interactions with the two plasma protease inhibitors antithrombin III (AT-III) or heparin cofactor II (HC-II) were investigated in the presence of oat spelts xylan sulfate (OSXS), sodium pentosan polysulfate (SP-54), and the results were compared with heparin and dermatan sulfate. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 4 | Addition of OSXS or SP-54 enhanced the complexation of thrombin with HC-II or with both AT-III and HC-II depending upon the concentration and the duration of the interactions of the sulfated compounds with plasma. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 5 | During the 30 s interaction, OSXS and SP-54 enhanced both AT-III-thrombin and HC-II-thrombin interaction while heparin was more selective and enhanced only the AT-III-thrombin interaction. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 6 | During the 30 s interaction, OSXS and SP-54 enhanced both AT-III-thrombin and HC-II-thrombin interaction while heparin was more selective and enhanced only the AT-III-thrombin interaction. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 7 | During the 30 s interaction, OSXS and SP-54 enhanced both AT-III-thrombin and HC-II-thrombin interaction while heparin was more selective and enhanced only the AT-III-thrombin interaction. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 8 | The complexations of AT-III-thrombin and HC-II-thrombin were reversed in the presence of 200 micrograms/ml of SP-54 during a 30 s interaction or in presence of 100 micrograms/ml of OSXS during a 2 min interaction. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 9 | The complexations of AT-III-thrombin and HC-II-thrombin were reversed in the presence of 200 micrograms/ml of SP-54 during a 30 s interaction or in presence of 100 micrograms/ml of OSXS during a 2 min interaction. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |