Pub. Date : 1995 Feb-May
PMID : 7588387
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dose-dependent increases (P < 0.05) in corticosterone concentration were observed when primary adrenal cells were incubated with different doses (10(-10) to 10(-8) M) of IL-1 alpha. | Corticosterone | interleukin 1 alpha | Rattus norvegicus |
| 2 | IL-1 alpha and IL-1 beta elevated corticosterone release after a 24 hr incubation period. | Corticosterone | interleukin 1 alpha | Rattus norvegicus |
| 3 | Although IL-1 alpha significantly increased (P < 0.05) prostaglandin E2 (PGE2) levels from primary adrenal cells, the presence of the cyclooxygenase inhibitor, indomethacin (10 microM) significantly inhibited IL-1 alpha-induced PGE2 secretion without altering the effect of IL-1 alpha on corticosterone release. | Corticosterone | interleukin 1 alpha | Rattus norvegicus |