Title : Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.

Pub. Date : 1995 Oct

PMID : 7586124






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The production of BMO from butadiene is mediated by CYP2E1 and, at high butadiene concentrations, by CYP2A6. bmo cytochrome P450 family 2 subfamily E member 1 Homo sapiens
2 These results implicate human CYP2E1 as a hepatic isoform responsible for the oxidation of BMO to BDE at low concentrations of BMO. bmo cytochrome P450 family 2 subfamily E member 1 Homo sapiens
3 These results implicate human CYP2E1 as a hepatic isoform responsible for the oxidation of BMO to BDE at low concentrations of BMO. bmo cytochrome P450 family 2 subfamily E member 1 Homo sapiens