Pub. Date : 1995 Sep 28
PMID : 7575672
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of the metalloproteinase inhibitors examined, only captopril, bestatin, and fosinoprilat had appreciable inhibitory activity for LTA4 hydrolase in disrupted epithelial cells. | Captopril | leukotriene A4 hydrolase | Homo sapiens |
| 2 | Concentration-inhibition curves to captopril, bestatin, and fosinoprilat revealed IC50 values of 430 microM, 7 microM, and 1 mM, respectively, for disrupted-cell LTA4 hydrolase activity. | Captopril | leukotriene A4 hydrolase | Homo sapiens |
| 3 | LTA4 hydrolase concentration-inhibition curves examined in intact cells with captopril, bestatin, and 1,10-O-phenanthroline revealed IC50 values of 63, 70, and 920 microM, respectively. | Captopril | leukotriene A4 hydrolase | Homo sapiens |