Title : Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.

Pub. Date : 1995 Sep 10

PMID : 7574675






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 As previously determined for the APPA-trypsin complex, the carbonyl carbon atom of APPA forms a covalent bond with O gamma of Ser195 of thrombin to yield a "transition-state" analog of the tetrahedral intermediate. Carbon coagulation factor II, thrombin Homo sapiens