Title : Beta-adrenergic control of c-fos expression in fetal and neonatal rat tissues: relationship to cell differentiation and teratogenesis.

Pub. Date : 1995 Aug

PMID : 7544033






2 Functional Relationships(s)
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1 In response to terbutaline, a beta 2-selective agonist, marked stimulation of c-fos was demonstrated in the liver, which contains beta 2-receptors, on Gestational Day 20, as well as on Postnatal Days 1 and 8. Terbutaline Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 In the heart, which contains predominantly beta 1-receptors, isoproterenol (a non-subtype-selective beta-agonist) was more effective that terbutaline, indicating that either receptor subtype can elicit stimulation of c-fos. Terbutaline Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus