Title : Cyclic adenosine monophosphate-dependent mechanisms induce von Willebrand factor expression in the Dami megakaryoblastic cell line.

Pub. Date : 1995 Feb

PMID : 7540877






4 Functional Relationships(s)
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1 Cyclic adenosine monophosphate-dependent mechanisms induce von Willebrand factor expression in the Dami megakaryoblastic cell line. Cyclic AMP von Willebrand factor Homo sapiens
2 It has been proposed that cyclic adenosine monophosphate (cAMP) is involved in the differentiation of several cell types and this study analysed whether von Willebrand factor (vWf) synthesis, which is a marker of the megakaryocyte maturation of these cells, would be enhanced by agents acting on cAMP formation. Cyclic AMP von Willebrand factor Homo sapiens
3 vWf synthesis paralleled the accumulation of cAMP in the cells. Cyclic AMP von Willebrand factor Homo sapiens
4 These data provide evidence that agents acting on cAMP metabolism induce vWf synthesis in the Dami megakaryoblastic cells. Cyclic AMP von Willebrand factor Homo sapiens