Title : Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells.

Pub. Date : 1995 Jun 9

PMID : 7539802






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Two additional serine residues, Ser-821 close to the major tyrosine autophosphorylation site in the kinase domain and Ser-959 in the carboxyl terminus are SCF-stimulated PKC-dependent phosphorylation sites. Tyrosine KIT ligand Homo sapiens
2 Both specific receptor tyrosine autophosphorylation and specific receptor-associated phosphatidylinositide 3"-kinase activity was increased approximately 2-fold in response to SCF in PAE cells stably expressing Kit/SCFR(S741A/S746A). Tyrosine KIT ligand Homo sapiens