Title : Combined effect of tin and lead on heme biosynthesis in rats.

Pub. Date : 1994 Nov

PMID : 7533708






3 Functional Relationships(s)
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1 The aim of the present study was to investigate the combined effect of tin (SnCl2) and lead Pb(CH3COO)2 on activity of heme biosynthesis enzymes [delta-aminolevulinic acid synthetase (ALA-S) and heme oxygenase] in liver and kidneys, as well as iron (Fe) and copper (Cu) concentration in serum of rats. Tin 5'-aminolevulinate synthase 1 Rattus norvegicus
2 The aim of the present study was to investigate the combined effect of tin (SnCl2) and lead Pb(CH3COO)2 on activity of heme biosynthesis enzymes [delta-aminolevulinic acid synthetase (ALA-S) and heme oxygenase] in liver and kidneys, as well as iron (Fe) and copper (Cu) concentration in serum of rats. Tin 5'-aminolevulinate synthase 1 Rattus norvegicus
3 Lead induced ALA-S in liver and kidney both after ip and po administration; tin, however, induced ALA-S only after ip administration in liver of rats. Tin 5'-aminolevulinate synthase 1 Rattus norvegicus