Protein Name 5'-aminolevulinate synthase 1
Organism Rattus norvegicus
Gene ID 65155
Gene Symbol

Alas1

UniProt P13195 (HEM1_RAT)
Relationships Total Number of functionally related compound(s) : 96
Total Number of Articles : 85
Description

5'-aminolevulinate synthase 1

Gene Summary

Enables 5-aminolevulinate synthase activity. Involved in several processes, including cellular response to insulin stimulus; response to herbicide; and response to nickel cation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in mitochondrial matrix. Biomarker of porphyria and pulmonary hypertension. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • 5-aminolevulinate synthase, non-specific, mitochondrial
  • 5-aminolevulinate synthase 1
  • 5-aminolevulinate synthase, nonspecific, mitochondrial
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Properties