Pub. Date : 1995 Jan
PMID : 7531117
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In support, this study shows that PGE2 inhibited myelin basic protein (MBP)-specific responses of proliferation and IL-2 production by continuously propagated lines of T-helper cells. | Dinoprostone | interleukin 2 | Rattus norvegicus |
| 2 | PGE2 did not block other measures of MBP-dependent activation, including induction of postactivation refractoriness in IL-2 production pathways, activation-dependent decreases in MBP reactivity, and activation-dependent increases in PGE2 sensitivity. | Dinoprostone | interleukin 2 | Rattus norvegicus |
| 3 | PGE2-mediated anergy was manifest as an intrinsic deficit rather than an acquired suppressive activity and was associated with reduced mitogenic responsiveness and a block in IL-2 production pathways. | Dinoprostone | interleukin 2 | Rattus norvegicus |