Protein Name interleukin 2
Organism Rattus norvegicus
Gene ID 116562
Gene Symbol

Il2

UniProt P17108 (IL2_RAT)
Relationships Total Number of functionally related compound(s) : 723
Total Number of Articles : 1040
Description

interleukin 2

Gene Summary

Enables carbohydrate binding activity; glycosphingolipid binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of T cell activation; protein kinase C-activating G protein-coupled receptor signaling pathway; and regulation of protein phosphorylation. Located in extracellular space. Used to study cystitis. Biomarker of allergic rhinitis; colorectal carcinoma; and tongue squamous cell carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Takayasu's arteritis; auditory system disease (multiple); autoimmune disease (multiple); carcinoma (multiple); and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • interleukin-2
  • IL-2
  • T-cell growth factor
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Properties