Title : Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate.

Pub. Date : 1994 Oct

PMID : 7530934






3 Functional Relationships(s)
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1 Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5"-phosphate. Pyridoxal Phosphate CD4 molecule Homo sapiens
2 Pyridoxal 5"-phosphate and related compounds were tested for their ability to inhibit gp120-CD4 interaction and human immunodeficiency virus infection in vitro. Pyridoxal Phosphate CD4 molecule Homo sapiens
3 The results show that pyridoxal 5"-phosphate is a unique CD4 antagonist whose antiviral potency derives from the presence of both lysine-reactive and anionic substituents. Pyridoxal Phosphate CD4 molecule Homo sapiens