Title : Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition.

Pub. Date : 1994 Aug 16

PMID : 7528680






1 Functional Relationships(s)
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Protein Name
Organism
1 The glycine site antagonist [3H]5,7-dichlorokynurenate bound with good affinity to all recombinant receptors (Kd approximately 50-100 nM), while glycine exhibited an affinity order of NR1-NR2C >> NR1 = NR1-NR2B = NR1-NR2D > NR1-NR2A. Glycine glutamate ionotropic receptor NMDA type subunit 2A Homo sapiens