Title : Role of O-linked carbohydrate chains on leukocyte cell membranes in platelet-induced leukocyte activation.

Pub. Date : 1994 Sep 16

PMID : 7521876






2 Functional Relationships(s)
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1 We previously reported that activated platelets stimulated neutrophils and monocytes to produce superoxide anion (O2-) through the interaction between P-selectin and its carbohydrate ligand, sialyl Lewis X (sLeX) (Nagata, K., Tsuji, T., Todoroki, N., Katagiri, Y., Tanoue, K., Yamazaki, H., Hanai N., and Irimura, T. (1993) J. Immunol. Carbohydrates selectin P Homo sapiens
2 These results strongly suggested that serine/threonine-linked carbohydrate chains containing sLex played an essential role in the P-selectin-mediated leukocyte activation. Carbohydrates selectin P Homo sapiens