Protein Name selectin P
Organism Homo sapiens
Gene ID 6403
Gene Symbol

SELP

UniProt P16109 (LYAM3_HUMAN), Q5R341 (Q5R341_HUMAN), Q6NUL9 (Q6NUL9_HUMAN), A0A024R8Y9 (A0A024R8Y9_HUMAN)
Relationships Total Number of functionally related compound(s) : 929
Total Number of Articles : 1543
Description

selectin P

Gene Summary

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

synonyms
  • P-selectin
  • CD62 antigen-like family member P
  • GMP-140
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Properties