Pub. Date : 1994 Jun 9
PMID : 7515480
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One such residue, occupying the EF1 position of the +3-binding pocket, is a Thr in the SH2 domain of the Src tyrosine kinase, but is predicted to be a Trp in the SH2 domain of the Sem-5/drk/Grb2 adaptor protein. | Threonine | growth factor receptor bound protein 2 | Homo sapiens |
| 2 | Here we report that changing this residue in the Src SH2 domain from Thr to Trp switches its selectivity to resemble that of the Sem-5/drk/Grb2 SH2 domain. | Threonine | growth factor receptor bound protein 2 | Homo sapiens |