Title : Assembly and regulation of NADPH oxidase and nitric oxide synthase.

Pub. Date : 1994 Feb

PMID : 7513523






1 Functional Relationships(s)
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1 Highlights include the demonstration that the G protein Rac 2 is required for NADPH oxidase activation, the finding that nitric oxide is a feedback inhibitor of nitric oxide synthase isoforms, and the discovery that the continuous catalytic activity of the immune/inflammatory nitric oxide synthase is due to strong calmodulin binding, which is independent of elevated calcium levels. Calcium Rac family small GTPase 2 Homo sapiens