Title : Tyrosine kinase inhibitors. 2. Synthesis of 2,2'-dithiobis(1H-indole-3-alkanamides) and investigation of their inhibitory activity against epidermal growth factor receptor and pp60v-src protein tyrosine kinases.

Pub. Date : 1994 Mar 4

PMID : 7510340






1 Functional Relationships(s)
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1 Inhibitory activity against EGF receptor tyrosine kinase was chain-length dependent, with the propanamides being the most effective. propionamide epidermal growth factor Homo sapiens