Pub. Date : 1995 Dec
PMID : 7493016
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The Sod2 gene for Mn-superoxide dismutase (MnSOD), an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation, was inactivated by homologous recombination. | Superoxides | superoxide dismutase 2, mitochondrial | Mus musculus |
2 | The Sod2 gene for Mn-superoxide dismutase (MnSOD), an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation, was inactivated by homologous recombination. | Superoxides | superoxide dismutase 2, mitochondrial | Mus musculus |
3 | These findings indicate that MnSOD is required for normal biological function of tissues by maintaining the integrity of mitochondrial enzymes susceptible to direct inactivation by superoxide. | Superoxides | superoxide dismutase 2, mitochondrial | Mus musculus |