Title : Kinetics of the hydroperoxide-dependent dealkylation reactions catalyzed by rabbit liver microsomal cytochrome P-450.

Pub. Date : 1980 Oct 25

PMID : 7430093






1 Functional Relationships(s)
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1 These results, which indicate that the reaction proceeds via an Ordered Bi Bi mechanism in which p-nitroanisole binds to the enzyme prior to the binding of t-butyl hydroperoxide, are discussed in relationship to the peroxidase-type mechanism which has been suggested for the action of cytochrome P-450. tert-Butylhydroperoxide cytochrome P-450 Oryctolagus cuniculus