Title : Post-translational glycosylation-induced activation of aglycoinsulin receptor accumulated during tunicamycin treatment.

Pub. Date : 1981 May 25

PMID : 7228853






1 Functional Relationships(s)
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1 Recovery of insulin binding activity after the removal of tunicamycin achieves 70-80% of control activity within 36 h. Concomitant with the withdrawal of tunicamycin, cells were shifted to medium containing heavy (greater than 95% 15N, 13C, 2H) amino acids after which Triton X-100-solubilized "light" and "heavy" insulin receptors were separated isopycnically on CsCl density gradients. 13c insulin Homo sapiens