Title : Evidence that physiologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.

Pub. Date : 1980 Dec 1

PMID : 7193053






1 Functional Relationships(s)
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1 Intact, but sham-operated female rats had 2- to 3-fold higher levels of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity than their male counterparts (15--21.5 vs. 6.7--8.7 nmol mevalonate/mg protein per h). Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus