Title : In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain.

Pub. Date : 1982 Sep 30

PMID : 7139278






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
2 The influence of the intrapallidal application of GABA-related compounds on the release of Met-enkephalin in the globus pallidus and the caudate nucleus in the two hemispheres was investigated in vivo in the cat. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
3 GABA (10-500 microM) reduced the local release of Met-enkephalin during its application but once the amino acid was removed from the superfusing fluid, an increase in the peptide release was observed. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
4 Opposite changes in Met-enkephalin release were also seen with the GABA antagonists, bicuculline methiodide (1 microM) and picrotoxin (10 microM), suggesting that the local regulation of Met-enkephalin release by GABA related compounds may be mediated by at least two types of GABA receptors. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
5 Opposite changes in Met-enkephalin release were also seen with the GABA antagonists, bicuculline methiodide (1 microM) and picrotoxin (10 microM), suggesting that the local regulation of Met-enkephalin release by GABA related compounds may be mediated by at least two types of GABA receptors. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
6 Opposite changes in Met-enkephalin release were also seen with the GABA antagonists, bicuculline methiodide (1 microM) and picrotoxin (10 microM), suggesting that the local regulation of Met-enkephalin release by GABA related compounds may be mediated by at least two types of GABA receptors. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
7 Opposite changes in Met-enkephalin release were also seen with the GABA antagonists, bicuculline methiodide (1 microM) and picrotoxin (10 microM), suggesting that the local regulation of Met-enkephalin release by GABA related compounds may be mediated by at least two types of GABA receptors. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens
8 In several cases, the unilateral pallidal application of GABA agonists and antagonists induced significant changes in Met-enkephalin release at distant structures. gamma-Aminobutyric Acid proopiomelanocortin Homo sapiens