Title : The fluorescence response of chlorotetracycline-loaded human neutrophils. Correlations with lysosomal enzyme release and evidence for a 'trigger pool' of calcium.

Pub. Date : 1982 Aug 27

PMID : 7126637






3 Functional Relationships(s)
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1 Similarly, neutrophils exposed to N-formylmethionylleucylphenylalanine and then restimulated by N-formylmethionylleucylphenylalanine in the presence of cytochalasin B secreted the azurophil granule enzyme beta-glucuronidase; release of the enzyme was also inversely related to the initial concentration of N-formylmethionylleucylphenylalanine. N-Formylmethionine Leucyl-Phenylalanine glucuronidase beta Homo sapiens
2 Both the second decrement in chlorotetracycline fluorescence and beta-glucuronidase release increased with time allowed between the two administrations of N-formylmethionylleucylphenylalanine. N-Formylmethionine Leucyl-Phenylalanine glucuronidase beta Homo sapiens
3 Secretion of beta-glucuronidase in response to N-formylmethionylleucylphenylalanine was also diminished by increasing the time of exposure to the initial stimulus of phorbol myristate acetate. N-Formylmethionine Leucyl-Phenylalanine glucuronidase beta Homo sapiens